Category Archives: Intern toolbox

EUH Dressler Conference: What are HIV elite controllers and HIV long-term nonprogressors?

The Bottom Line: Long-term nonprogressors (LTNP) account for 1-5% of HIV-infected individuals characterized by documented infection for more than 7-10 years, a stable CD4+ T cell count over 500/mm3 and low viremia in the absence of antiretroviral treatment. They are able … Continue reading

Posted in Background question, Diagnosis, EUH, Intern toolbox, Teaching pearls

EUH Dressler Conference: What is the most appropriate timeframe for administering IV fluids to patients with sepsis or septic shock?

The Bottom Line: The Surviving Sepsis Guideline states 30cc/kg within first 3 hours for sepsis or shock, as defined by new Sepsis definitions (Singer et al, 2016). References: Leisman D, Wie B, Doerfler M, Bianculli A, et al. Association of … Continue reading

Posted in EUH, Intern toolbox, Therapy

EUH Dressler Conference: How a differential diagnosis tool held up to Emory minds.

The Bottom Line: Isabel, a differential diagnosis generator, was used by a clinical informationist as residents and faculty talked through a case study. The ultimate diagnosis, Hodgkin’s lymphoma, was listed in Isabel’s #2 spot of possible diagnoses (see screenshot below). … Continue reading

Posted in Diagnosis, EUH, Intern toolbox

What information can I learn from looking at an ROC curve?

Receiver operating characteristic curves graph the true positive rate against the false positive rate for the possible cutpoints of a diagnostic test.  Use ROC curve to… Compare accuracy of test at different cutpoints.  Curve close to left and upper border … Continue reading

Posted in Applying evidence, Intern toolbox

Review of pulmonary hypertension

Holger, M. Nef.  Pulmonary Hypertension: Updated classification and management of pulmonary hypertension Heart 2010;96:552-559 doi:10.1136/hrt.2008.156299 Pulmonary arterial hypertension is characterised by a progressive increase of pulmonary pressure and resistance leading to right heart failure. Pulmonary hypertension is categorised into five … Continue reading

Posted in Background question, EUHMidtown, Grady, Intern toolbox, Miscellaneous

Interpreting data about diagnostic tests

Scherokman B.  Selecting and interpreting diagnostic tests.  The Permanente Journal.  1997;1(2):4-7. Succinct explanation of how sensitivity, predictive value, etc., applies to the impact of a test on the diagnosis and the selection of tests in a particular diagnostic workup.

Posted in Intern toolbox

Diabetic ketoacidosis (DKA) & hyperglycemic hyperosmolar non-ketotic syndrome (HHNK)

Umpierrez GEMD, Khajavi MMD, Kitabchi AEPMD. Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Nonketotic Syndrome. American Journal of the Medical Sciences. 1996;311(5):225-233. Umpierrez GE, Smiley D, Kitabchi AE. Narrative review: ketosis-prone type 2 diabetes mellitus. Ann Intern Med. 2006 Mar 7;144(5):350-7. Palmer … Continue reading

Posted in EUH, Intern toolbox