Category Archives: EUH

EUH Morning Report: In patients with acute alcoholic hepatitis, does steroid therapy increase the risk of GI bleeding compared to no use of steroids?

The Bottom Line: For patients with acute alcoholic hepatitis, there isn’t literature to answer the question of whether steroid therapy increases risk of GI bleeding compared to no use of steroids. For patients with non-acute alcoholic liver disease who do not have concomitant … Continue reading

Posted in Applying evidence, EUH, Therapy | Tagged

EUH Krakow Conference: Does empagliflozin cause ketoacidosis?

Bottom Line: An analysis of FDA Adverse Event Reporting System (FAERS) data and three case reports provide evidence that sodium glucose cotransporter 2 (SGLT2) inhibitors (canagliflozin, dapagliflozin, and empagliflozin) cause ketoacidosis. FAERS data A search was done of the FAERS data … Continue reading

Posted in EUH, Therapy

EUH Krakow Conference: What are all of the causes of anion gap acidosis and are there mnemonics by which to remember them?

Bottom Line: Causes of anion gap metabolic acidosis are broken down into the following categories: overproduction of acid due to ketoacidosis or lactic acidosis, underexcretion of acid (such as due to advanced renal failure/chronic kidney disease (uremia)), cell lysis (such … Continue reading

Posted in Background question, EUH

EUH Krakow Conference: What are the diagnostic criteria for Henoch-Schonlein purpura (HSP)?

The Bottom Line: European League Against Rheumatism/Paediatric Rheumatology International Trials Organisation/Paediatric Rheumatology European Society (EULAR/PRINTO/PRES) criteria for diagnosis of HSP include both: purpura or petechiae not related to thrombocytopenia with lower limb predominance (or demonstration of immunoglobulin A [IgA] deposits … Continue reading

Posted in Background question, Diagnosis, EUH

EUH Krakow Conference: What are the causes of leukocytoclastic vasculitis?

The Bottom Line: About half of cases are idiopathic. The remainder are most often either drug induced or post infectious. Viral upper respiratory infection or streptococcal pharyngitis frequently precede the onset of IgA vasculitis by 1 to 2 weeks. 40% … Continue reading

Posted in Background question, Diagnosis, EUH

EUH Dressler Conference: What are the presentations of nonconvulsive status epilepticus?

The Bottom Line: Nonconvulsive status epilepticus (NCSE) refers to a group of highly heterogeneous clinical conditions lasting more than 30 minutes, in which continuous or recurrent electrographic seizure activity results in nonconvulsive clinical features. NCSE in adults represents a constellation … Continue reading

Posted in Background question, Diagnosis, EUH

EUH Morning Report: What is the ideal diuretic dosing strategy for diuretics in a patient admitted from home with acute decompensated HF and already on home diuretics?

The Bottom Line: In managing patients admitted with heart failure exacerbation, the DOSE trial confirmed that furosemide (Lasix) intermittent bolus is equivalent to continuous drip, making continuous drip management unnecessary in nearly all situations. Furthermore, symptoms were similar in high dose … Continue reading

Posted in Applying evidence, EUH, Therapy