Category Archives: EUH

EUH Krakow Conference: What is the diagnosis and treatment for complement-mediated thrombotic microangiopathy?

The Bottom Line: The clinical presentation of thrombotic microangtiopathy (TMA) reflects hemolysis and ischemic organ dysfunction, and depends on the underlying disease etiology. AKI is a common manifestation of TMAs although it is rarely a severe feature of TTP. The initial … Continue reading

Posted in Diagnosis, EUH, Therapy

EUH Dressler Conference: What is the epidemiology of legionella pneumonia?

The Bottom Line: Legionella pneumonia accounts for 2-7% of community-acquired pneumonia (CAP) worldwide. In the U.S., legionella infections accounted for 1.3 per 100,000 cases between 2011-2013. Of the 1,426 cases reported in the U.S between 2011-2013: 79% in patients > 50 … Continue reading

Posted in Background question, Diagnosis, EUH

EUH Dressler Conference: What is the sensitivity/specificity of the legionella urine antigen test?

The Bottom Line: The sensitivity and specificity of the Legionella urine antigen test are as high as 90% and 99%, respectively. The test for Legionella pneumophila detects only serogroup 1, but this serogroup accounts for most community-acquired cases of Legionnaires’ disease in the United States … Continue reading

Posted in Diagnosis, EUH

EUH Krakow Conference: What are the differential diagnoses for a pleural effusion with low pleural fluid glucose?

The Bottom Line: Low pleural fluid glucose (<60 mg/dL) indicates the pleural effusion is most likely caused by one of the following: Empyema Complicated parapneumonic effusion Malignant pleural effusion Tuberculous pleural effusion Rheumatoid pleural effusion Other rare causes of low … Continue reading

Posted in Diagnosis, EUH

EUH Hunt Conference: What is the treatment for insulinomas?

The Bottom Line:  Diet: small frequent meals throughout the day and in them idle of the night to prevent hypoglycemia (DynaMed Plus, 2017). Medications: Diazoxide is administered to suppress insulin release. For incurable islet cell carcinomas, steptozocin is the best … Continue reading

Posted in EUH, Prognosis, Therapy

EUH Krakow Conference: Treatment of thrombotic thrombocytopenic purpura (TTP).

The Bottom Line: Treat TTP as a medical emergency.  For full treatment details, see the TTP section in DynaMed Plus. Acquired TTP: Initiate plasma exchange Give methylprednisolone or high-dose oral prednisolone If plasma exchange is unavailable/delayed, consider large plasma infusions if … Continue reading

Posted in EUH, Therapy

EUH Morning Report: Does my patient have hepatomegaly?

The Bottom Line: Hepatomegaly should be considered for patients with known or suspected liver disorders, malignancy, or congestive heart failure. When there is a suspicion of liver disease, it’s recommended that clinicians forgo the scratch test and use percussion to … Continue reading

Posted in Diagnosis, EUH