The Bottom Line: Isabel, a differential diagnosis generator, was used by a clinical informationist as residents and faculty talked through a case study. The ultimate diagnosis, Hodgkin’s lymphoma, was listed in Isabel’s #2 spot of possible diagnoses (see screenshot below). Emory residents were able to specify the diagnosis as nodular sclerosis Hodgkin’s lymphoma. It must be noted that the residents and faculty were not aware of Isabel’s participation until after they reached the final diagnosis.
Summary: Isabel is a differential diagnosis support tool designed to help physicians construct or broaden their differential. In this case study, the clinical features presented as the chief complaint were entered and a list of possible diagnoses was generated. As the case progressed, additional clinical features were added when appropriate.