Category Archives: Background question

EUH Hunt Conference: What is plastic bronchitis?

The Bottom Line: Plastic bronchitis (PB) is an uncommon pulmonary disease characterized by production of cohesive and branching casts filling the airways. The diagnosis of PB is confirmed by a history of expectoration of branching airways casts, or by removing … Continue reading

Posted in Background question, Diagnosis, EUH, Teaching pearls

EUH Dressler Conference: What is the pathophysiology of disseminated intravascular coagulation (DIC)?

The Bottom Line: DIC is a systemic pathophysiologic process and not a single disease entity. The massive tissue factor stimulus results in excess intravascular thrombin, which overcomes the anticoagulant systems and leads to thrombosis. Because of consumption of coagulation factors … Continue reading

Posted in Background question, EUH

EUH Krakow Conference: Are there instances of pancreatic ductal leaks into pleural effusions?

The Bottom Line: Yes. Pancreatic ductal leaks, or pancreatic duct disruption, are often  complications of acute pancreatitis (AP) or chronic pancreatitis (CP). However, no published cases were identified regarding ductal leaks into pleural effusions as result of trauma. References: King … Continue reading

Posted in Background question, EUH

EUH Krakow Conference: What causes elevated amylase in pleural effusions?

The Bottom Line: The pleural fluid amylase is elevated in patients with pleural effusions secondary to esophageal perforation, pancreatic disease, or malignant disease (Broaddus and Light, 2016). References: Broaddus VC, and Light RW. Pleural Effusion. In Murray and Nadal’s Textbook … Continue reading

Posted in Background question, Diagnosis, EUH

EUH Krakow Conference: What is the life expectancy for Chronic Myeloid Leukemia (CML)?

The Bottom Line: Five-year survival for ages less than 45 at diagnosis is 88.8%. For males of all races, it is 87.5%: white males 88.7%, black males 73.5%. Reference: National Cancer Institute. SEER Cancer Statistics Review (CSR), 1975-2014. 2017: p.24. Available at: https://seer.cancer.gov/csr/1975_2014/results_merged/topic_survival.pdf. … Continue reading

Posted in Background question, EUH

EUH Dressler Conference: How frequently does angioedema coincide with Hodgkin’s lymphoma?

The Bottom Line: Rarely. Normal level of C1 esterase inhibitor proteins in association with angioedema due to lymphoproliferative disease is a rare and an uncommon finding caused by antibodies produced from the underlying disease (Gunatilake and Wimalaratna, 2014). Acquired angioedema … Continue reading

Posted in Background question, EUH

EUH Dressler Conference: What is the serologic course of Hepatitis B?

The Bottom Line: Hepatitis B serologic testing involves measurement of several hepatitis B virus (HBV)-specific antigens and antibodies. Different serologic “markers” or combinations of markers are used to identify different phases of HBV infection and to determine whether a patient … Continue reading

Posted in Background question, EUH, Therapy