Category Archives: Miscellaneous

EUH Krakow Conference: What is the sensitivity of the 4th generation test for acute HIV infection?

The Bottom Line:  A study involving 86,836 participants found the Abbott Architect HIV Ag/Ab Combo Assay to have a 79.8% sensitivity and 99.9% specificity with a positive predictive value of 59% (Peters et al, 2016). Reference: Peters PJ, Westheimer E, … Continue reading

Posted in Diagnosis, EUH, Miscellaneous

EUH Resident Report: What are sources for syncope rules?

Evaluation of Guidelines in Syncope Study (EGSYS) syncope score: Calculate by QxMD (app is freely available for Android and Apple devices), EMERG CDRs (app is freely available for Android devices) Osservatorio Epidemiologico sulla Sincope nel Lazio (OESIL) risk score: American … Continue reading

Posted in Applying evidence, EUH, Miscellaneous

How common is is acquired Factor VIII deficiency?

The Bottom line: A rare disorder, Acquired hemophilia A has an incidence of approximately 1 per million a year. The mortality rate is high at more than 20%. AHA occurs due to autoantibodies against coagulation factor VIII which results in … Continue reading

Posted in EUHMidtown, Miscellaneous

How long is the window to see blood on a noncontrasted CT head scan?

Piccini & Nilsson: The Osler Medical Handbook, 2nd ed CT is up to 95% sensitive for detecting acute SAH if performed hours after aneurysmal rupture, but sensitivity decreases about 10% per day after rupture.

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Evidence on physical capability and mortality, early use of palliative care, and tools for assessing delirium in ICU patients

Objectively measured physical capability levels and mortality: systematic review and meta-analysis. BMJ. 2010 Sep 9;341:c4467. doi: 10.1136/bmj.c4467. Systematic review of studies on association of various measures of physical activity and mortality in community populations Early palliative care for patients with … Continue reading

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Negative Predictive Value of LDH in Pneumocystis Pneumonia

Chief Complaint: “I can’t breathe” Question: What is the negative predictive value of LDH in PCP? Article: Speich R, Opravil M, Weber R, Hess T, Luethy R, Russi EW. Prospective evaluation of a prognostic score for pneumocystis cariini pneumonia in … Continue reading

Posted in Diagnosis, EUHMidtown, Grady, Miscellaneous

Review of pulmonary hypertension

Holger, M. Nef.  Pulmonary Hypertension: Updated classification and management of pulmonary hypertension Heart 2010;96:552-559 doi:10.1136/hrt.2008.156299 Pulmonary arterial hypertension is characterised by a progressive increase of pulmonary pressure and resistance leading to right heart failure. Pulmonary hypertension is categorised into five … Continue reading

Posted in Background question, EUHMidtown, Grady, Intern toolbox, Miscellaneous