Bottom Line: The authors created a “Pathways Service” to link patient care to scientific inquiry by attempting to fill gaps in knowledge regarding the biology behind patients’ medical problems. Residents refer patients on their service to the program “if they … Continue reading
The Bottom Line: A study involving 86,836 participants found the Abbott Architect HIV Ag/Ab Combo Assay to have a 79.8% sensitivity and 99.9% specificity with a positive predictive value of 59% (Peters et al, 2016). Reference: Peters PJ, Westheimer E, … Continue reading
The Bottom line: A rare disorder, Acquired hemophilia A has an incidence of approximately 1 per million a year. The mortality rate is high at more than 20%. AHA occurs due to autoantibodies against coagulation factor VIII which results in … Continue reading
Piccini & Nilsson: The Osler Medical Handbook, 2nd ed CT is up to 95% sensitive for detecting acute SAH if performed hours after aneurysmal rupture, but sensitivity decreases about 10% per day after rupture.
Objectively measured physical capability levels and mortality: systematic review and meta-analysis. BMJ. 2010 Sep 9;341:c4467. doi: 10.1136/bmj.c4467. Systematic review of studies on association of various measures of physical activity and mortality in community populations Early palliative care for patients with … Continue reading
Chief Complaint: “I can’t breathe” Question: What is the negative predictive value of LDH in PCP? Article: Speich R, Opravil M, Weber R, Hess T, Luethy R, Russi EW. Prospective evaluation of a prognostic score for pneumocystis cariini pneumonia in … Continue reading