Category Archives: Core Conference

EUH Core Conference: What are the pros and cons of using different antidepressive medications?

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Medication summaries created by Dr. Lauren Gensler.

  • Fluoxetine (SSRI)
    • Dosages: 10-20mg (starting), 40mg (therapeutic), 80mg (maximum)
    • Drug profile:Sexual side effects, activating, no withdrawal syndrome
    • Pharmacology: ½ life 2-3 days, but active metabolite 2-3 weeks
      • Metabolized: 2D6
      • Inhibits: 2D6 (potent)
  • Sertraline (SSRI)
    • Dosages: 50mg (starting), 100mg (therapeutic), 200mg (maximum)
    • Drug profile:
      • Mildly activating, N/V
    • Pharmacology:
      • ½ life 26 hours
      • Metabolized: 2B6
      • Inhibits: 2D6 (mod)
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