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Category Archives: Therapy
The Bottom Line: In a study of hospitalized patients with spontaneous bacterial peritonitis (SBP), Kim et al (2014) concluded: Patients who receive delayed paracentesis (DP) had a higher in-hospital mortality (27% vs 13%) compared with those who received early paracentesis (EP). … Continue reading
EUH Hunt Conference: What trials have been done on early vs. later initiation of ARTs in the hospital for opportunistic infections in the setting of HIV?
The Bottom Line: Karim et al (2010): An open-label randomized controlled trial in Durban, South Africa to determine optimal timing of ART initiation in relation to TB treatment. Acid-fast bacilli (AFB) smear positive tuberculosis patients with HIV infection and CD4+ counts … Continue reading
Bottom Line: An analysis of FDA Adverse Event Reporting System (FAERS) data and three case reports provide evidence that sodium glucose cotransporter 2 (SGLT2) inhibitors (canagliflozin, dapagliflozin, and empagliflozin) cause ketoacidosis. FAERS data A search was done of the FAERS data … Continue reading
The Bottom Line: Treatment guidelines for hospital-acquired aspiration pneumonia no definitive evidence to inform optimal antibiotic regimen antibiotic choice typically based on setting and concern for anaerobic infection treatment should be based on suspected pathogens pathogenic role of anaerobes and … Continue reading