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Category Archives: Therapy
Bottom Line: An analysis of FDA Adverse Event Reporting System (FAERS) data and three case reports provide evidence that sodium glucose cotransporter 2 (SGLT2) inhibitors (canagliflozin, dapagliflozin, and empagliflozin) cause ketoacidosis. FAERS data A search was done of the FAERS data … Continue reading
The Bottom Line: Treatment guidelines for hospital-acquired aspiration pneumonia no definitive evidence to inform optimal antibiotic regimen antibiotic choice typically based on setting and concern for anaerobic infection treatment should be based on suspected pathogens pathogenic role of anaerobes and … Continue reading
The Bottom Line: Thrombolysis may be considered in selected intermediate-risk PE patients who have evidence of RV dysfunction or myocardial damage or in PE who may be clinically worsening or not improving with anticoagulation, and/or based on patient values or … Continue reading
EUH Dressler Conference: What is the most appropriate timeframe for administering IV fluids to patients with sepsis or septic shock?
The Bottom Line: The Surviving Sepsis Guideline states 30cc/kg within first 3 hours for sepsis or shock, as defined by new Sepsis definitions (Singer et al, 2016). References: Leisman D, Wie B, Doerfler M, Bianculli A, et al. Association of … Continue reading