Category Archives: Therapy

EUH Morning Report: Review of microscopic colitis

Bottom Line: “Microscopic colitis is a common cause of chronic watery diarrhea, particularly in the elderly. The accompanying symptoms, which include abdominal pain and fatigue, can markedly impair patients’ quality of life. Diagnosis is based upon characteristic histologic findings of … Continue reading

Posted in Background question, Diagnosis, Therapy

EUH Dressler Case Conference: What is the definition of heart failure with mid-range ejection fraction (HFmrEF), which is also called intermediate ejection fraction and borderline heart failure with preserved left ventricular (LV) ejection fraction (HFpEF)? Do patients benefit from typical HFrEF therapies?

Bottom Line: In a meta-analysis, Zheng, Chan, Nabeebaccus, et al. state, “The latest European Society of Cardiology guidelines introduced the term heart failure with mid-range ejection fraction (HFmrEF), categorising an intermediate group of patients with an LV ejection fraction of … Continue reading

Posted in Diagnosis, EUH, Therapy | Tagged

EUH Dressler Case Conference: Review of cardiac sarcoidosis

Bottom Line: Increased awareness and diagnostic techniques are the primary reasons for the exponential increase in the prevalence of cardiac sarcoidosis during the last decade. More evidence is needed to determine optimal management. First-line treatment is corticosteroids; authors recommend also using … Continue reading

Posted in Background question, EUH, Therapy | Tagged

EUH Hunt Conference: Review of Meigs’ Syndrome

Bottom Line: Meigs’ syndrome is also known as Meigs syndrome or Demons-Meigs syndrome. It is characterized by a triad of ascites, pleural effusion, and benign ovarian fibroma, which is a rare triad. “Meigs syndrome…is a diagnosis of exclusion only after ovarian carcinoma … Continue reading

Posted in Background question, EUH, Prognosis, Therapy | Tagged ,

EUH Krakow Conference: What is the diagnosis and treatment for complement-mediated thrombotic microangiopathy?

The Bottom Line: The clinical presentation of thrombotic microangtiopathy (TMA) reflects hemolysis and ischemic organ dysfunction, and depends on the underlying disease etiology. AKI is a common manifestation of TMAs although it is rarely a severe feature of TTP. The initial … Continue reading

Posted in Diagnosis, EUH, Therapy

EUH Hunt Conference: What is the treatment for insulinomas?

The Bottom Line:  Diet: small frequent meals throughout the day and in them idle of the night to prevent hypoglycemia (DynaMed Plus, 2017). Medications: Diazoxide is administered to suppress insulin release. For incurable islet cell carcinomas, steptozocin is the best … Continue reading

Posted in EUH, Prognosis, Therapy

EUH Krakow Conference: Treatment of thrombotic thrombocytopenic purpura (TTP).

The Bottom Line: Treat TTP as a medical emergency.  For full treatment details, see the TTP section in DynaMed Plus. Acquired TTP: Initiate plasma exchange Give methylprednisolone or high-dose oral prednisolone If plasma exchange is unavailable/delayed, consider large plasma infusions if … Continue reading

Posted in EUH, Therapy