EUH Morning Report: What are extraintestinal manifestations of inflammatory bowel disease (IBD)?

The Bottom Line:

“Extraintestinal manifestations (EIMs) are commonly reported in IBD patients. It has been reported that 6.2% to 46.6% of IBD patients exhibit one or more EIMs either before or after the diagnosis of IBD.” (Ferri, 2021).

Extraintestinal manifestions of ulcerative colitis (UC) and Crohn disease (CD) include:

  • Joint manifestations: Axial arthritis (ankylosing spondylitis [AS] and sacroiliitis [SI]) and peripheral arthropathy
  • Skin manifestations: Pyoderma gangrenosum, erythema nodosum, sweet syndrome, and psoriasis
  • Hepatobiliary manifestation: Primary sclerosing cholangitis (PSC)
  • Ocular manifestations: Uveitis, episcleritis, scleritis, and iritis
  • Vascular manifestation: Thromboembolism
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