The Bottom Line:
“Extraintestinal manifestations (EIMs) are commonly reported in IBD patients. It has been reported that 6.2% to 46.6% of IBD patients exhibit one or more EIMs either before or after the diagnosis of IBD.” (Ferri, 2021).
Extraintestinal manifestions of ulcerative colitis (UC) and Crohn disease (CD) include:
- Joint manifestations: Axial arthritis (ankylosing spondylitis [AS] and sacroiliitis [SI]) and peripheral arthropathy
- Skin manifestations: Pyoderma gangrenosum, erythema nodosum, sweet syndrome, and psoriasis
- Hepatobiliary manifestation: Primary sclerosing cholangitis (PSC)
- Ocular manifestations: Uveitis, episcleritis, scleritis, and iritis
- Vascular manifestation: Thromboembolism