Tag Archives: Oncology

VA Resident Report: What is the management strategy of Kaposi Sarcoma and pneumocystis pneumonia in a HIV positive patient?

The Bottom Line: The management of pulmonary KS is challenging. There is a risk of precipitating IRIS upon initiating cART. Chemotherapy can also cause further immunosuppression and increase the risk of further infections. In many of these patients, initiation of … Continue reading

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VA Resident Report: Can depleted uranium rounds cause cancer?

The risk of fatal cancer for the maximally exposed Level I veteran is 1.4% (upper bound of 3.5%). Almost all of the DU-induced cancer risk is associated with the risk incurred for lung cancer. DU fragments are predicted to increase … Continue reading

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VA Resident Report: What is the association between squamous cell carcinoma and acquired factor VIII?

Following surgery for the patient in this case study, the tumor nor the coagulation inhibitor has recurred after 6 months’ follow-up. While it is possible that the inhibitor may have remitted spontaneously or remained in remission because of the therapy … Continue reading

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VA Resident Report: What is the etiology and therapy options for Postobstructive community-acquired pneumonia?

The Bottom Line: This study encourages more limited antibiotic use in patients with PO-CAP. Our experience has been that when patients fail to respond to a first course of antibiotics, physicians repeat sputum cultures, which now are contaminated with newly … Continue reading

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Review of advancements in treating Multiple Myeloma (MM)

The Bottom Line: New diagnostic criteria, a Revised International Staging System, and the approval of three drugs (four others pending approval) have greatly advanced the treatment, diagnosis, staging, risk-stratification and management of MM. These changes, as well as others detailed … Continue reading

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Weight gain and oxygen failure in ATRA differentiation syndrome

Supportive measures are also crucial in the correct management of differentiation syndrome. In the PETHEMA protocols, furosemide is usually administered to treat signs or symptoms of fluid overload. Some cases with refractory acute renal failure and/or fluid overload may need … Continue reading

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How to distinguish multiple myeloma and amyloidosis

Multiple myeloma is a malignant plasma cell tumor, which ranks second in terms of prevalence among the hematologic malignancies. Diagnostic criteria includes occurrence of a monoclonal component detectable on serum and/or urine electrophoresis, light chain restricted bone marrow plasmacytosis, and … Continue reading

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