Tag Archives: Neurology

Neurologic testing in diagnosis of syncope

Bottom line: Unless there are additional neurologic signs or symptoms, neurologic testing for syncope is rarely helpful. Source Linzer, M, et al. “Diagnosing syncope. Part 1: Value of history, physical examination, and electrocardiography. Clinical Efficacy Assessment Project of the American … Continue reading

Posted in Diagnosis, EUH | Tagged ,

Review of tuberculosis meningitis

Thwaites, Guy E, Ronaldvan Toorn, and JohanSchoeman. “Tuberculous meningitis: more questions, still too few answers.” Lancet neurology 12.10 (2013):999-1010.  

Posted in Background question, Diagnosis, EUH, Therapy | Tagged

When should a head CT be performed prior to a lumbar puncture?

Lumbar puncture/Procedure considerations/Neuroimaging in Dynamed The section on Testing to Consider Prior to Performing an LP in DynaMed’s entry for lumbar puncture summarizes two prospective cohort studies and lists clinical findings such as age and aspects of clinical history and … Continue reading

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What are the neurologic sequelae of NSAID toxicity, and do these include aseptic meningitis?

The Bottom Line: One of the important neurologic side-effects attributed to the over-use of NSAIDs is aseptic meningitis. Reference: Auriel et al.  Nonsteroidal anti-inflammatory drugs exposure and the central nervous system.  Handb Clin Neurol 2014;119:577-84. Summary: CNS effects of NSAID toxicity range … Continue reading

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McDonald criteria for diagnosis of multiple sclerosis

Bottom line: Table 3 from study by the Magnims European research network provides estimated data (95% confidence interval) for sensivity, specificity, accuracy, positive predictive value, positive likelihood ratio, and negative likelihood ratio for old and new McDonald criteria (divided up by overall criteria (dissemination … Continue reading

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Responsive Nerve Simulator (RNS) for Epilepsy

How it works “The RNS® System (NeuroPace, Mountain View, CA) provides responsive cortical stimulation via a cranially implanted programmable neurostimulator connected to 1 or 2 recording and stimulating depth or subdural cortical strip leads that are surgically placed in the … Continue reading

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Efficacy and timing of steroids for meningitis

Bottom line: Cochrane systematic review found support for use of corticosteroids in meningitis patients in high-income countries. Administering corticosteroids with the first dose of antibiotics as opposed to after the first dose led to similar results with regard to mortality … Continue reading

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