Tag Archives: Endocrinology & Metabolism

VA Resident Report: Review of pheochromocytoma and imaging

The Bottom Line: Imaging studies are important for tumor localization and lineation of its extent. They are also important in diagnosing multiple primary tumors and/or metastatic lesions in patients with various genetic disorders. The approach to surgical removal may depend … Continue reading

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EUHM Resident Report: What is the incidence of muscle twitch in hypercalcemia

The novel family of genetically encoded calcium indicators, named ‘Twitch’ sensors, fulfill the majority of criteria and represent a major improvement over most existing indicators. The name of the indicators originates from the fact that their calcium sensor is derived … Continue reading

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VA Resident Report: Treatment of insulinoma

The Bottom Line: Treatment of insulinoma consists of controlling symptoms of hypoglycemia, followed by tumor localization. Neuroendocrine Tumors Jensen, Robert T., Norton, Jeffrey A., Oberg, Kjell Sleisenger and Fordtran’s Gastrointestinal and Liver Disease, Chapter 33, Pages 501-541.e15 Copyright © 2016 … Continue reading

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VA Resident Report: What is the association of hyperprolactinemia in association with hypothyroidism?

The Bottom Line This study showed prevalence of hyperprolactinemia in subclinical hypothyroidism is notable and this disorder is more common in female subclinical hypothyroidism than the men. Bahar, Adele, et al. “Hyperprolactinemia in association with subclinical hypothyroidism.” Caspian journal of … Continue reading

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Is there sufficient evidence for the subcutaneous administration of insulin for diabetic ketoacidosis?

The Bottom Line: In patients with mild-to-moderate DKA, subcutaneous injections of insulin lispro every 1-2h offer a feasible alternative to continuous intravenous infusions of regular insulin, and should now be evaluated in larger, more appropriately powered studies. Reference: Vincent M, Nobécourt E. … Continue reading

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Correction of serum sodium [Na+] in hyponatremia

Bottom line: Verbalis states that the goal is a minimum correction of 4-8 mmol/L per day; if the risk of osmotic demyelination syndrome (ODS) is high then a lower goal of 4-6 mmol/L is recommended. Recommended limits not to exceed are … Continue reading

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Diagnostic tests for pheochromocytoma and paraganglioma

Endocrine Society guideline states, “plasma metanephrines or urinary fractionated metanephrines are considered tests of choice.” See tables 4 and 5 in the guideline for data on sensitivity and specificity for the tests of choice. DynaMed states, “Medications that may cause … Continue reading

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