Category Archives: Diagnosis

EUH Hunt Conference: What is the sensitivity of cytology tests of pleural effusion and ascites?

Bottom Line: Sensitivity of ascitic cytology is approximately 60%, and the sensitivity of pleural effusion cytology is approximately 50%. References: Karoo RO, Lloyd TD, Garcea G, Redway HD, Robertson GS. How valuable is ascitic cytology in the detection and managent … Continue reading

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EUH Hunt Conference: What is the diagnostic workup of cardiac sarcoidosis?

The Bottom Line: Cardiac sarcoidosis has varied presentations depending on the extent and location of cardiac granulomas. Patients may have AV block, heart failure, or sudden cardiac death. The disease should be considered especially in young or middle-aged women who present … Continue reading

Posted in Diagnosis, EUH

EUH Hunt Conference: What is the sensitivity/specificity of ACE levels in cardiac sarcoidosis?

The Bottom Line:  Serum levels of angiotensin-converting enzyme (ACE) can be helpful in the diagnosis of sarcoidosis. However, the test has somewhat low sensitivity and specificity. Elevated levels of ACE are reported in 60% of patients with acute disease and only … Continue reading

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EUH Krakow Conference: What is the diagnosis and treatment for complement-mediated thrombotic microangiopathy?

The Bottom Line: The clinical presentation of thrombotic microangtiopathy (TMA) reflects hemolysis and ischemic organ dysfunction, and depends on the underlying disease etiology. AKI is a common manifestation of TMAs although it is rarely a severe feature of TTP. The initial … Continue reading

Posted in Diagnosis, EUH, Therapy

EUH Dressler Conference: What is the epidemiology of legionella pneumonia?

The Bottom Line: Legionella pneumonia accounts for 2-7% of community-acquired pneumonia (CAP) worldwide. In the U.S., legionella infections accounted for 1.3 per 100,000 cases between 2011-2013. Of the 1,426 cases reported in the U.S between 2011-2013: 79% in patients > 50 … Continue reading

Posted in Background question, Diagnosis, EUH

EUH Dressler Conference: What is the sensitivity/specificity of the legionella urine antigen test?

The Bottom Line: The sensitivity and specificity of the Legionella urine antigen test are as high as 90% and 99%, respectively. The test for Legionella pneumophila detects only serogroup 1, but this serogroup accounts for most community-acquired cases of Legionnaires’ disease in the United States … Continue reading

Posted in Diagnosis, EUH

EUH Krakow Conference: What are the differential diagnoses for a pleural effusion with low pleural fluid glucose?

The Bottom Line: Low pleural fluid glucose (<60 mg/dL) indicates the pleural effusion is most likely caused by one of the following: Empyema Complicated parapneumonic effusion Malignant pleural effusion Tuberculous pleural effusion Rheumatoid pleural effusion Other rare causes of low … Continue reading

Posted in Diagnosis, EUH