Category Archives: Applying evidence

EUH Resident Report: What are sources for syncope rules?

Evaluation of Guidelines in Syncope Study (EGSYS) syncope score: Calculate by QxMD (app is freely available for Android and Apple devices), EMERG CDRs (app is freely available for Android devices) Osservatorio Epidemiologico sulla Sincope nel Lazio (OESIL) risk score: American … Continue reading

Posted in Applying evidence, EUH, Miscellaneous

EUH Resident Report: The China Antihypertensive Trial in Acute Ischemic Stroke (CATIS) Study

The Bottom Line: The effect of antihypertensive treatment in patients with acute ischemic stroke is uncertain. This RCT concluded that bloodpressure reduction with antihypertensive medications, compared with the absence of hypertensive medication, did not reduce the likelihood of death and … Continue reading

Posted in Applying evidence, Background question, EUH | Tagged ,

Intermittent vs Continuous Proton Pump Inhibitor Therapy for High-Risk Bleeding Ulcers A Systematic Review and Meta-analysis

Sachar, Hamita, KetaVaidya, and LorenLaine. “Intermittent vs continuous proton pump inhibitor therapy for high-risk bleeding ulcers: a systematic review and meta-analysis.” JAMA internal medicine 174.11 (2014):1755-62. Conclusion: “Intermittent PPI therapy is comparable to the current guideline-recommended regimen of intravenous bolus … Continue reading

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Outcomes for near syncope/presyncope and syncope

Bottom line: Patients who present to the emergency department with near syncope and syncope are likely to have similar prevalence, etiology, prognosis, critical interventions, and adverse outcomes. Patients with near syncope are less likely to be admitted. Sources Grossman, Shamai … Continue reading

Posted in Applying evidence, EUH, Prognosis | Tagged ,

Polypharmacy – number of medication-related issues in relation to number of medications

Bottom line: In cases of polypharmacy, the number of medication-related issues increases with the number of medications. Sources Steinman, Michael A, et al. “Polypharmacy and prescribing quality in older people.” Journal of the American Geriatrics Society 54.10 (2006):1516-23. ‚ÄúThis is … Continue reading

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Diantamoeba fragilis as a cause of gastrointestinal (GI) clinical symptoms such as diarrhea

Bottom line: Numerous reports from all over the world describe associations between diantamoeba fragilis and various GI symptoms, such as diarrhea. Evidence: Stark D, Barratt J, Roberts T, Marriott D, Harkness J, Ellis J. A review of the clinical presentation … Continue reading

Posted in Applying evidence, Diagnosis, EUH | Tagged ,

Diagnostic tests for pheochromocytoma and paraganglioma

Endocrine Society guideline states, “plasma metanephrines or urinary fractionated metanephrines are considered tests of choice.” See tables 4 and 5 in the guideline for data on sensitivity and specificity for the tests of choice. DynaMed states, “Medications that may cause … Continue reading

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