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Author Archives: Lisa
Bottom Line: An analysis of FDA Adverse Event Reporting System (FAERS) data and three case reports provide evidence that sodium glucose cotransporter 2 (SGLT2) inhibitors (canagliflozin, dapagliflozin, and empagliflozin) cause ketoacidosis. FAERS data A search was done of the FAERS data … Continue reading
EUH Krakow Conference: What are all of the causes of anion gap acidosis and are there mnemonics by which to remember them?
Bottom Line: Causes of anion gap metabolic acidosis are broken down into the following categories: overproduction of acid due to ketoacidosis or lactic acidosis, underexcretion of acid (such as due to advanced renal failure/chronic kidney disease (uremia)), cell lysis (such … Continue reading
See page 90 for a map showing the North America distributions of histoplasma, blastomyces, coccidioides, and Cryptococcus gattii (c. gattii). Source: Hage CA. Fungal lung disease. In: Schraufnagel DE, ed. Breathing in America: Diseases, Progress, and Hope. American Thoracic Society (ATS); 2010:89-97.
EUH Resident Report: In arterial thromboembolic events, what percentage have cardiogenic sources versus other sources?
Bottom line: Three studies have attributed arterial thromboembolic events to cardiogenic sources in 33%, 51%, and 66% of cases. Studies of larger populations are needed. Sources: Mural thrombus of the aorta: an important, frequently neglected cause of large peripheral emboli. … Continue reading
Bottom line: Evidence that is of low and moderate quality, respectively, is used in a guideline that recommends against routine vitamin K supplementation for patients taking vitamin K antagonists (VKAs) (grade 2c) and against routine vitamin K supplementation for patients taking VKAs … Continue reading