VA Resident Report: Review of pheochromocytoma and imaging

The Bottom Line: Imaging studies are important for tumor localization and lineation of its extent. They are also important in diagnosing multiple primary tumors and/or metastatic lesions in patients with various genetic disorders. The approach to surgical removal may depend considerably on the location, extent, and the association of the tumor with nearby anatomical structures. Imaging studies, especially functional studies are also useful adjuncts in confirming diagnosis of the tumor when biochemical investigations are ambiguous or not available in patients with clinical suspicion of the tumor. Computed tomography, contrast enhanced CT, and magnetic resonance imaging are now routinely complemented by functional imaging using various radiotracers such as 123I-metaiodobenzylguanidine and 111In-DTPA-pentetreotide.

References: Ramachandran, R., & Rewari, V. (n.d.). Current perioperative management of pheochromocytomas. Indian Journal of Urology : IJU : Journal of the Urological Society of India., 33(1), 19-25.

Summary: Surgical removal of PCC and PGL alleviates the signs, symptoms and probable end organ damage due to catecholamine hypersecretion. Preoperative optimization has played an important role in decreasing the high incidence of perioperative morbidity and mortality historically associated with these surgical procedures. Alpha-receptors blockade, especially with selective alpha-1 receptor antagonists, is thus vital in these patients preoperatively

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