EUH Resident Report: What are indications for anticoagulants for primary prevention of left ventricular thrombosis?

Bottom line: Indications for anticoagulants for primary prevention of left ventricular thrombosis include patients with the following traits: large anterior infarctions (particularly in the anterior location), heart failure, and high embolic risk (including those with echocardiographic evidence of mobile and protruding thrombi, severe left ventricular dysfunction, or prior emboli).

Sources (two review articles):

Antithrombotic therapy in left ventricular thrombosis and systemic embolism. L L Cregler. The American heart journal, 1992, Vol.123(4 Pt 2), p.1110-1114.

Antithrombotic therapy in acute myocardial infarction: prevention of venous, left ventricular and coronary artery thromboembolism. B Stein, V Fuster. The American journal of cardiology, 1989, Vol.64(4), p.33B-40B.

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About Lisa

I have been a Clinical Informationist (aka Medical Librarian) for Emory University since September 2013. Prior to that, I was a Medical Librarian for Lincoln Memorial University (LMU) from March 2007 to August 2013 and served its DeBusk College of Osteopathic Medicine, Caylor School of Nursing, and allied health programs. From January 2002 - March 2007, I served the Medical Assisting (MA), Occupational Therapy Assistant, Physical Therapy Assistant, Radiologic Technologist, and Nursing programs at South College in Knoxville, Tennessee. I graduated from The University of Tennessee School of Information Sciences with a Master of Science degree in December 2000.
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