Detection of neuroendocrine syndromes

From Dynamed:

Carcinoid tumors

From the menu on the left, click on “Diagnosis” then “Imaging Studies”

Somatostatin receptor scintigraphy (OctreoScan) reported to improve localization of primary tumors and metastases
-among patients with carcinoid of small intestine (where conventional imaging including magnetic resonance imaging [MRI] was negative)
-OctreoScan identified 16% primary lesions and 33% metastatic lesions

In-pentetreotide might detect more metastatic lesions than 123I-MIBG in patients with carcinoid
based on retrospective study
-54 patients had imaging with both 111In-pentetreotide and 123I-MIBG
-46 had histologically proven metastatic NETs
-2 had breast carcinoid without other tumor located
-5 had clinical and/or biochemical evidence of recurrence of prior histologically proven NET
-1 had clinical and biochemical evidence of NET not seen on conventional imaging

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