What is the standard definition of acute renal failure?

Bottom line:  According to ADQI classification, renal failure is defined as

  • changes in serum creatinine: increase in serum creatine 3 times baseline and GFR decrease by 75% OR a serum creatinine ≥4 mg/dl
  • changes in urine output: Urine output < 0.3 ml/kg/h x 24 hours OR anuria x 12 hours
  • changes in both

Bellomo R, et al.  Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group.  Critical Care 2004, 8:R204-R212.

Fig 1. (p. R204) Proposed classification scheme for acute renal failure.  Classification of borderline, injury and failure through ESKD based on changes in creatinine, urine output or both.

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About Amy

Clinical Informationist at EUH Branch Library
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