What is the evidence behind prolactin in the diagnosis of seizures?

Schapira: Neurology and Clinical Neuroscience, 1st ed.
Copyright © 2008 Mosby, An Imprint of Elsevier

Prolactin release peaks 15 minutes after the end of a GTCS or of a temporal lobe complex partial seizure, reflecting the propagation of ictal discharges into the hypothalamus. The relatively low magnitude of this release needs to be compared with a baseline value obtained in the same individual at the same hour on another day.

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