When stool osmolality reveals an osmotic gap, how can it help in differentiating between secretory and osmotic etiologies?

Bottom line:  In the setting of diarrhea, if [stool osmolality – 2 x (stool Na +  stool K)] > 100,  then there is an osmotic gap and the cause of the diarrhea is osmotic.

Chronic diarrhea.  In:  DynaMed.   See Stool Studies in the Diagnosis Section.


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Clinical Informationist at EUH Branch Library
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