What is the approach to hyponatremia?

The Bottom Line: Ideal treatment requires balancing risks of hypotonicity against those of therapy. Symptoms and their severity largely determine the pace of correction.

Horacio J. Adrogué, M.D., and Nicolaos E. Madias, M.D Hyponatremia. N Engl J Med 2000; 342:1581-1589 May 25, 2000

Summary: Hyponatremia is a decrease in the serum sodium concentration below 136 mmol per liter.

TABLE 1. Causes of Hypotonic Hyponatremia Page 1583

Figure 2. Effects of Hyponatremia on the Brain and Adaptive Responses. Page 1584

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