Is there an association between strep pneumo and arthritis?

The Bottom Line: Of 2407 cases of septic arthritis from large series, 156 (6%) were caused by Streptococcus pneumoniae.

Reference: Ross JJ, Saltzman CL, Carling P, Shapiro DS.  Pneumococcal septic arthritis: review of 190 cases.  Clin Infect Dis. 2003 Feb 1;36(3):319-27.

Summary: Mortality was 19% among adults and 0% among children. Pneumococcal bacteremia was the strongest predictor of mortality. At least 1 knee was involved in 56% of adults. Polyarticular disease (36%) and bacteremia (72%) were more common among adults with septic arthritis caused by S. pneumoniae than among adults with other causative organisms. Only 50% of adults with pneumococcal septic arthritis had another focus of pneumococcal infection, such as pneumonia. Functional outcomes were good in 95% of patients.

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