What is the mechanism of a Low BUN/Cr ratio?

Bottom Line: Several clinical circumstances can lead to a decreased serum urea nitrogen-creatinine ratio.  Therefore, it is helpful to use this ratio and to remember the significance of a decreased ratio.
Reference: Jurado F, Mattix H.  The decreased serum urea nitrogen-creatinine ratio.  Arch Intern Med (1998) 158:2509-11.
Summary: The serum urea nitrogen-creatinine ratio is a well-known diagnostic tool.  Conditions such as malnutrition, hepatic disease, and rhabdomyolysis may be recognized by a decreased serum urea nitrogen-creatinine ratio.

Repost from July 22, 2010

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