What are the guidelines for liver transplantation in patients with extrahepatic malignancy?

Liver transplant (LT) “candidates with a prior extrahepatic malignancy should have received definitive treatment with adequate tumor-free survival prior to listing for LT (1-B).” Extrahepatic malignancy is listed as a contraindication for LT in Table 4.

Primary source: Martin P, DiMartini A, Feng S, Brown R Jr, Fallon M. Evaluation for liver transplantation in adults: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation. Hepatology. 2014 Mar;59(3):1144-65.

DynaMed Plus lists the following contraindication for liver transplantation: “active cancer, but liver transplant can be done in patient with prior extrahepatic malignancy who has received definitive treatment and has adequate tumor-free survival to presume cure (AASLD Strong recommendation, Moderate-quality evidence).”

Updated 2/24/2016 ldt


About Amy

Clinical Informationist at EUH Branch Library
This entry was posted in Background question, EUH. Bookmark the permalink.