What are the diagnostic strategies for cardiac sarcoidosis?

Mehta D, Lubitz SA, Frankel Z, Wisnivesky JP, Einstein AJ, Goldman M, Machac J, Teirstein A. Cardiac involvement in patients with sarcoidosis: diagnostic and prognostic value of outpatient testing.  Chest. 2008 Jun;133(6):1426-35.

Table 1.  Prespecified Abnormalities in Clinical Testing, p. 1427

Table 2.  Modified Guidelines for the Diagnosis of CS from the JMHW, p. 1428

Conclusion: CS is common among patients with sarcoidosis.  A structured clinical assessment incorporating advanced cardiac imaging with PET scanning or CMRI is more sensitive than the established criteria for the identification of CS.  Sarcoidal lesions seen on CMRI or PET scanning do not predict arrhythmias in ambulatory patients with preserved cardiac function, who appear to be at low risk for short-term mortality.

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