Triester SL, et al. A meta-analysis of the yield of capsule endoscopy compared to other diagnostic modalities in patients with obscure gastrointestinal bleeding. Am J Gastroenterol. 2005 Nov;100(11):2407-18. PubMed PMID: 16279893.
Objective: To evaluate the yield of small bowel findings with CE in patients with OGIB compared to other modalities using meta-analysis.
Methods: Searched for prospective studies comparing the yield of CE to other modalities in patients with OGIB that were conducted within 2 weeks of the CE.
Results: 20 studies were identified with 14 comparing capsule to push enteroscopy (N=396). All but one blinded clinicians in the study to the results of the diagnostic tests. Figure 2 (p. 2411) contains forest plot summarizing the percent yield of significant findings. For all studies the yield for CE was 63% and for push enteroscopy was 28%).
3 studies compared capsule to small bowel barium radiography (N=117). Overall, the diagnostic yield for the capsule was 67% versus 8% for barium radiography.