According to the section for medication-related hyperkalemia in Brenner & Rector’s The Kidney, 10th edition, the following drugs can induce hyperkalemia by impairing renin-aldosterone elaboration/fuction:
- Cyclooxygenase inhibitors (NSAIDs)
- Cyclosporine and tacrolimus
- Epithelial sodium channel inhibitors (amiloride, trimethoprim, and pentamidine)
- Angiotensin-converting enzyme inhibitors
- Mineralocorticoid and angiotensin antagonists (ARBs (angiotensin receptor blockers))
Ben Salem et al. Drug-induced hyperkalemia. Drug Saf. 2014 Sep;37(9):677-92.
This review article addresses drugs included in Brenner & Rector’s book and provides an overiew of the mechanisms involved.
Updated 2/13/2016
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