How does inpatient treatment for deep vein thrombosis compare to outpatient treatment?

Othieno R, et al. Home versus in-patient treatment for deep vein thrombosis. Cochrane Database of Systematic Reviews 2007, Issue 3. Art. No.: CD003076 Full-text Systematic Review

To compare the incidence and outcome of complications of venous thromboembolism (VTE) when treated in the patient’s home as against the standard in-patient regimen commonly practiced

Pooling of data from 6 RCTs (total N=1702; unblinded; randomized to home treatment or hospital treatment; all participants had adequate home support

With home treatment as the intervention and hospital treatment as the control, risk ratios for…
* Recurrence of VTE: Risk Ratio (M-H, Fixed, 95% CI) 0.61 [0.42, 0.90]
* Major bleeding: Risk Ratio (M-H, Fixed, 95% CI) 0.67 [0.33, 1.36]
* Minor bleeding: Risk Ratio (M-H, Fixed, 95% CI) 1.29 [0.94, 1.78]
* Mortality: Risk Ratio (M-H, Fixed, 95% CI) 0.72 [0.45, 1.15]
Forest plot pooling results of studies comparing Fig. 1, recurrence of VTE; Fig. 2, major bleeding; Fig. 3, minor bleeding; Fig. 4, mortality.


About Amy

Clinical Informationist at EUH Branch Library
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