What is the criteria for diagnosing scleroderma and what are the recommendations for managing scleroderma renal crisis?

From Current Diagnosis & Treatment: Rheumatology (McGraw-Hill, 3rd edition, 2013)

“Most frequent symptoms are in (descending order):
Raynaud phenomenon
gastroesophageal reflux with or without dysmotility
skin changes
swollen fingers
arthralgias”

Other factors:
* “A negative antinuclear antibody test (by indirect immunofluorescence) makes the diagnosis of scleroderma very unlikely.
* The degree of skin involvement is highly variable. Many patients with limited scleroderma have only subtle cutaneous findings (eg, mild sclerodactyly).
* The current classification criteria do not include many patients with milder forms of scleroderma.
* Some patients may have overlapping clinical features with other systemic autoimmune rheumatic disorders such as polymyositis/dermatomyositis, Sjögren syndrome, systemic lupus erythematosus, and rheumatoid arthritis.”

In DynaMed Plus:

See article entitled “Systemic sclerosis”

For management of renal crisis, see section for renal symptoms within the medications section of the treatment section of the article entitled “Systemic sclerosis”

Updated 2/11/2016 ldt

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About Amy

Clinical Informationist at EUH Branch Library
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